The Center for Cancer & Blood Disorders



Current Clinical Trials as of July 18, 2011

We welcome your participation in a clinical trial for cancer research. If you would like more information on the clinical trials listed below, please call Joyce Wallace, Research Manager, at 817.759.7022 or send an email to jwallace@txcc.com.

Diagnosis Study Name Brief Study Description
Triple Negative Breast BRE 01-08 Neoadjuvant weekly nab-paclitaxel (Abraxane) plus Carboplatin followed by Doxorubicin plus Cyclophosphamide with Bevacizumab added concurrently to chemo for palpable and operable triple negative breast cancer
Metastatic Breast BRE 161 Amrubicin as 2nd or 3rd Line Treatment for Patients with HER2 Negative Metastatic Breast Cancer
Colorectal GI 134 FOLFOXIRI plus Panitumumab as 1st Line Therapy for KRAS Wild-type Patients with Metastatic Colorectal Cancer with Liver Metastases Only
Diffuse Large B-cell Lymphoma Novartis – RAD001N2301 Randomized, CHOP-R +/- RAD 001
Peripheral T-Cell Lymphoma COMPLETE Registry Primary objective is to describe, in detail, patterns of care for patients with peripheral T-cell lymphoma, by treatment setting.
Multiple Myeloma Novartis CLBH589D2308 Randomized, double-blind, placebo controlled phase III study of panobinostat in combination with bortezomib and dexamethasone in patients with relapsed multiple myeloma
1st Line NSCLC
Poor Performance Status Patients
SCRI
LUN 196- TOPPS
Randomized phase II trial of Pemetrexed vs. Pemetrexed/Bevacizumab vs. Pemetrexed/Carboplatin/Bevacizumab in patients with Stage IIIB/IV NSCLC and ECOG performance status 2

1st Line NSCLC Lilly H3E-US-S130 Randomized, Open-Label study of Pemetrexed + Carboplatin in patients w/ Nonsquamous Histology
1st Line NSCLC
Squamous
BiPar
20090321 (EFC11553)
Randomized, Phase III Trial of Gemcitabine/Carboplatin with or without BSI-201 (SAR240550) (a PARP1 Inhibitor) in Patients with Previously Untreated Stage IV Squamous NSCLC
Stage IV NSCLC Lilly I4T-MC-JVBA Randomized, double-blind, phase III study of Docetaxel and Ramucirumab vs. Docetaxel and placebo in the treatment of stage IV NSCLC following disease progression after one prior platinum-based therapy
Ovarian GYN 19 Randomized Study of Paclitaxel/Carboplatin with or without Sorafenib in the 1st Line Treatment of Patients with Stage III/IV Epithelial Ovarian Cancer
Prostate BMS- CA184043 Randomized, Double Blinded, Ipilimumab vs. Placebo post Radiotherapy
Unknown Primary UNKPRI 20 Chemotherapy Based on Molecular Profiling Diagnosis for Patients with Carcinoma of Unknown Primary Site
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